Cheesy Macaroni and Hamburger Casserole 🍝🧀 – The Ultimate Comfort Dinner
Thank you so much for stopping by! Today, I’m sharing a true family-favorite recipe: Cheesy Macaroni and Hamburger Casserole.

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Ingredients
Instructions
- Cook the pasta Boil macaroni according to package directions until al dente. Drain and set aside.
- Brown the beef In a large skillet, cook ground beef and chopped onion until beef is browned and onion is softened. Drain excess fat. Season with garlic powder and onion powder.
- Make it cheesy Stir in Velveeta cubes, cheddar cheese soup, sour cream, Parmesan, and milk. Mix until everything is smooth and combined.
- Assemble the casserole Add cooked macaroni to the beef mixture and stir well. Pour into a greased 9×13-inch casserole dish.
- Top it off Lay slices of American cheese evenly across the top.
- Bake Bake at 350°F (175°C) for about 20–25 minutes, until bubbly and golden.
Thank you so much for stopping by! Today, I’m sharing a true family-favorite recipe: Cheesy Macaroni and Hamburger Casserole. This dish is the definition of cozy comfort food — a bubbling casserole filled with tender macaroni, seasoned ground beef, and layer upon layer of creamy, melty cheese.
It’s hearty enough for weeknight dinners, kid-approved, and the kind of meal that makes everyone at the table go back for seconds. Honestly, this casserole is a hug on a plate!
Why You’ll Love Cheesy Macaroni and Hamburger Casserole
- Simple ingredients – pantry and fridge staples you probably already have.
- So cheesy – Velveeta, cheddar soup, American cheese, AND Parmesan.
- Family-friendly – picky eaters love it just as much as adults.
- Great for make-ahead – prep in advance and bake when ready.
What Does It Taste Like?
Think of creamy stovetop mac and cheese — but heartier, richer, and with savory seasoned ground beef stirred right in. It’s cheesy, indulgent, and perfectly comforting, like a cross between cheeseburger pasta and a baked casserole.
Ingredients for Cheesy Macaroni and Hamburger Casserole
- 1 lb. ground beef
- 1 onion, chopped
- 2 cups macaroni noodles (uncooked)
- 8 oz. Velveeta cheese, cubed
- 1 can cheddar cheese soup
- ½ tsp onion powder
- 1 tsp garlic powder
- 8 oz. sour cream
- ½ cup Parmesan cheese, grated
- ¼ cup milk
- 8 slices American cheese
Tools You’ll Need
- Large skillet
- Medium saucepan
- 9×13-inch casserole dish
- Mixing bowls
- Wooden spoon or spatula
Ingredient Swaps & Additions
- Swap ground beef with ground turkey or chicken for a lighter version.
- Add sautéed mushrooms, peas, or broccoli for extra veggies.
- Use shredded cheddar instead of American cheese if you prefer.
- Spice it up with red pepper flakes or jalapeños.
How to Make Cheesy Macaroni and Hamburger Casserole
- Cook the pasta Boil macaroni according to package directions until al dente. Drain and set aside.
- Brown the beef In a large skillet, cook ground beef and chopped onion until beef is browned and onion is softened. Drain excess fat. Season with garlic powder and onion powder.
- Make it cheesy Stir in Velveeta cubes, cheddar cheese soup, sour cream, Parmesan, and milk. Mix until everything is smooth and combined.
- Assemble the casserole Add cooked macaroni to the beef mixture and stir well. Pour into a greased 9×13-inch casserole dish.
- Top it off Lay slices of American cheese evenly across the top.
- Bake Bake at 350°F (175°C) for about 20–25 minutes, until bubbly and golden.
What to Serve with Cheesy Macaroni and Hamburger Casserole
- A crisp green salad with Italian dressing
- Garlic bread or Texas toast
- Steamed broccoli or roasted green beans
Storage & Reheating
- Fridge: Store leftovers covered for up to 4 days.
- Freezer: Wrap tightly and freeze for up to 2 months.
- Reheat: Warm in oven at 325°F until heated through, or microwave individual portions.
Final Thoughts
This Cheesy Macaroni and Hamburger Casserole is one of those recipes that just feels like home. It’s rich, comforting, and perfect for feeding a hungry family on a busy night. Bonus? It reheats beautifully for leftovers!
If you loved this recipe, you’ll also enjoy my Chicken Asparagus Casserole and Baked Cream Cheese Spaghetti for more comforting dinner ideas.
📌 Don’t forget to pin this recipe and share your cheesy casserole creations with me on Pinterest — I’d love to see how it turned out for you!
Nutritional Information (Approx. per serving, 1 of 8)
- Calories: 430
- Protein: 23g
- Carbs: 31g
- Fat: 24g
- Fiber: 2g
Tips for Success
- Cook macaroni just until al dente so it doesn’t get mushy while baking.
- For a crispy topping, sprinkle with breadcrumbs before baking.
- Let casserole rest for 5 minutes after baking so it sets before serving.
